diff --git a/CHANGELOG.md b/CHANGELOG.md
index 411c0cdbfb..cda3e2e191 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -13,6 +13,7 @@
 - [#3564](https://github.com/poanetwork/blockscout/pull/3564) - Staking welcome message
 
 ### Fixes
+- [#3715](https://github.com/poanetwork/blockscout/pull/3715) - Pending transactions sanitizer process
 - [#3710](https://github.com/poanetwork/blockscout/pull/3710) - Missing @destination in bridged-tokens template
 - [#3707](https://github.com/poanetwork/blockscout/pull/3707) - Fetch bridged token price by address of foreign token, not by symbol
 - [#3686](https://github.com/poanetwork/blockscout/pull/3686) - BSC bridged tokens detection fix
diff --git a/apps/explorer/lib/explorer/chain.ex b/apps/explorer/lib/explorer/chain.ex
index 99ab68c4cc..b1c074a297 100644
--- a/apps/explorer/lib/explorer/chain.ex
+++ b/apps/explorer/lib/explorer/chain.ex
@@ -1618,6 +1618,10 @@ defmodule Explorer.Chain do
     Repo.one!(query, timeout: :infinity) || 0
   end
 
+  def fetch_block_by_hash(block_hash) do
+    Repo.get(Block, block_hash)
+  end
+
   @spec fetch_sum_coin_total_supply_minus_burnt() :: non_neg_integer
   def fetch_sum_coin_total_supply_minus_burnt do
     {:ok, burn_address_hash} = string_to_address_hash("0x0000000000000000000000000000000000000000")
@@ -2748,6 +2752,16 @@ defmodule Explorer.Chain do
     )
   end
 
+  def pending_transactions_list do
+    query =
+      from(transaction in Transaction,
+        where: is_nil(transaction.block_hash) and (is_nil(transaction.error) or transaction.error != "dropped/replaced")
+      )
+
+    query
+    |> Repo.all()
+  end
+
   @doc """
   The `string` must start with `0x`, then is converted to an integer and then to `t:Explorer.Chain.Hash.Address.t/0`.
 
diff --git a/apps/explorer/lib/explorer/chain/import/runner/blocks.ex b/apps/explorer/lib/explorer/chain/import/runner/blocks.ex
index 6a85041620..b8d67208ce 100644
--- a/apps/explorer/lib/explorer/chain/import/runner/blocks.ex
+++ b/apps/explorer/lib/explorer/chain/import/runner/blocks.ex
@@ -273,10 +273,10 @@ defmodule Explorer.Chain.Import.Runner.Blocks do
     |> Enum.map(& &1.number)
   end
 
-  defp lose_consensus(repo, hashes, consensus_block_numbers, changes_list, %{
-         timeout: timeout,
-         timestamps: %{updated_at: updated_at}
-       }) do
+  def lose_consensus(repo, hashes, consensus_block_numbers, changes_list, %{
+        timeout: timeout,
+        timestamps: %{updated_at: updated_at}
+      }) do
     acquire_query =
       from(
         block in where_invalid_neighbour(changes_list),
diff --git a/apps/indexer/config/dev.exs b/apps/indexer/config/dev.exs
index 8d53da7f69..85c3bb8abe 100644
--- a/apps/indexer/config/dev.exs
+++ b/apps/indexer/config/dev.exs
@@ -21,6 +21,11 @@ config :logger, :addresses_without_code,
   path: Path.absname("logs/dev/indexer/addresses_without_code.log"),
   metadata_filter: [fetcher: :addresses_without_code]
 
+config :logger, :pending_transactions_to_refetch,
+  level: :debug,
+  path: Path.absname("logs/dev/indexer/pending_transactions_to_refetch.log"),
+  metadata_filter: [fetcher: :pending_transactions_to_refetch]
+
 variant =
   if is_nil(System.get_env("ETHEREUM_JSONRPC_VARIANT")) do
     "ganache"
diff --git a/apps/indexer/config/prod.exs b/apps/indexer/config/prod.exs
index 896b38a979..5929e71942 100644
--- a/apps/indexer/config/prod.exs
+++ b/apps/indexer/config/prod.exs
@@ -23,6 +23,11 @@ config :logger, :addresses_without_code,
   path: Path.absname("logs/prod/indexer/addresses_without_code.log"),
   metadata_filter: [fetcher: :addresses_without_code]
 
+config :logger, :pending_transactions_to_refetch,
+  level: :debug,
+  path: Path.absname("logs/prod/indexer/pending_transactions_to_refetch.log"),
+  metadata_filter: [fetcher: :pending_transactions_to_refetch]
+
 variant =
   if is_nil(System.get_env("ETHEREUM_JSONRPC_VARIANT")) do
     "parity"
diff --git a/apps/indexer/lib/indexer/block/realtime/fetcher.ex b/apps/indexer/lib/indexer/block/realtime/fetcher.ex
index ac064f4878..2b96f6ffe3 100644
--- a/apps/indexer/lib/indexer/block/realtime/fetcher.ex
+++ b/apps/indexer/lib/indexer/block/realtime/fetcher.ex
@@ -140,6 +140,11 @@ defmodule Indexer.Block.Realtime.Fetcher do
      }}
   end
 
+  # don't handle other messages (e.g. :ssl_closed)
+  def handle_info(_, state) do
+    {:noreply, state}
+  end
+
   defp subscribe_to_new_heads(%__MODULE__{subscription: nil} = state, subscribe_named_arguments)
        when is_list(subscribe_named_arguments) do
     case EthereumJSONRPC.subscribe("newHeads", subscribe_named_arguments) do
diff --git a/apps/indexer/lib/indexer/pending_transactions_sanitizer.ex b/apps/indexer/lib/indexer/pending_transactions_sanitizer.ex
new file mode 100644
index 0000000000..74a47232a9
--- /dev/null
+++ b/apps/indexer/lib/indexer/pending_transactions_sanitizer.ex
@@ -0,0 +1,124 @@
+defmodule Indexer.PendingTransactionsSanitizer do
+  @moduledoc """
+  Periodically checks pending transactions status in order to detect that transaction already included to the block
+  And we need to re-fetch that block.
+  """
+
+  use GenServer
+
+  require Logger
+
+  import EthereumJSONRPC, only: [json_rpc: 2, request: 1]
+
+  alias Explorer.{Chain, Repo}
+  alias Explorer.Chain.Import.Runner.Blocks
+
+  @interval :timer.hours(3)
+
+  defstruct interval: @interval,
+            json_rpc_named_arguments: []
+
+  def child_spec([init_arguments]) do
+    child_spec([init_arguments, []])
+  end
+
+  def child_spec([_init_arguments, _gen_server_options] = start_link_arguments) do
+    default = %{
+      id: __MODULE__,
+      start: {__MODULE__, :start_link, start_link_arguments}
+    }
+
+    Supervisor.child_spec(default, [])
+  end
+
+  def start_link(init_opts, gen_server_opts \\ []) do
+    GenServer.start_link(__MODULE__, init_opts, gen_server_opts)
+  end
+
+  def init(opts) when is_list(opts) do
+    state = %__MODULE__{
+      json_rpc_named_arguments: Keyword.fetch!(opts, :json_rpc_named_arguments),
+      interval: opts[:interval] || @interval
+    }
+
+    Process.send_after(self(), :sanitize_pending_transactions, state.interval)
+
+    {:ok, state}
+  end
+
+  def handle_info(
+        :sanitize_pending_transactions,
+        %{interval: interval, json_rpc_named_arguments: json_rpc_named_arguments} = state
+      ) do
+    Logger.debug("Start sanitizing of pending transactions",
+      fetcher: :pending_transactions_to_refetch
+    )
+
+    sanitize_pending_transactions(json_rpc_named_arguments)
+
+    Process.send_after(self(), :sanitize_pending_transactions, interval)
+
+    {:noreply, state}
+  end
+
+  defp sanitize_pending_transactions(json_rpc_named_arguments) do
+    pending_transactions_list_from_db = Chain.pending_transactions_list()
+
+    pending_transactions_list_from_db
+    |> Enum.with_index()
+    |> Enum.each(fn {pending_tx, ind} ->
+      pending_tx_hash_str = "0x" <> Base.encode16(pending_tx.hash.bytes, case: :lower)
+
+      with {:ok, result} <-
+             %{id: ind, method: "eth_getTransactionReceipt", params: [pending_tx_hash_str]}
+             |> request()
+             |> json_rpc(json_rpc_named_arguments) do
+        if result do
+          block_hash = Map.get(result, "blockHash")
+
+          Logger.debug(
+            "Transaction #{pending_tx_hash_str} already included into the block #{block_hash}. We should invalidate consensus for it in order to re-fetch transactions",
+            fetcher: :pending_transactions_to_refetch
+          )
+
+          fetch_block_and_invalidate(block_hash)
+        end
+      end
+    end)
+
+    Logger.debug("Pending transactions are sanitized",
+      fetcher: :pending_transactions_to_refetch
+    )
+  end
+
+  defp fetch_block_and_invalidate(block_hash) do
+    case Chain.fetch_block_by_hash(block_hash) do
+      %{number: number, consensus: consensus} ->
+        Logger.debug(
+          "Corresponding number of the block with hash #{block_hash} to invalidate is #{number} and consensus #{
+            consensus
+          }",
+          fetcher: :pending_transactions_to_refetch
+        )
+
+        invalidate_block(number, consensus)
+
+      _ ->
+        Logger.debug(
+          "Block with hash #{block_hash} is not yet in the DB",
+          fetcher: :pending_transactions_to_refetch
+        )
+    end
+  end
+
+  defp invalidate_block(number, consensus) do
+    if consensus do
+      opts = %{
+        timeout: 60_000,
+        timestamps: %{updated_at: DateTime.utc_now()}
+      }
+
+      Blocks.lose_consensus(Repo, [], [number], [], opts)
+    end
+  end
+end
diff --git a/apps/indexer/lib/indexer/supervisor.ex b/apps/indexer/lib/indexer/supervisor.ex
index d7f8f09ec1..14c2a97a2a 100644
--- a/apps/indexer/lib/indexer/supervisor.ex
+++ b/apps/indexer/lib/indexer/supervisor.ex
@@ -11,6 +11,7 @@ defmodule Indexer.Supervisor do
     Block,
     CalcLpTokensTotalLiqudity,
     PendingOpsCleaner,
+    PendingTransactionsSanitizer,
     SetAmbBridgedMetadataForTokens,
     SetOmniBridgedMetadataForTokens
   }
@@ -128,6 +129,7 @@ defmodule Indexer.Supervisor do
       {CoinBalanceOnDemand.Supervisor, [json_rpc_named_arguments]},
       {TokenTotalSupplyOnDemand.Supervisor, [json_rpc_named_arguments]},
       {TokenBalanceOnDemand.Supervisor, [json_rpc_named_arguments]},
+      {PendingTransactionsSanitizer, [[json_rpc_named_arguments: json_rpc_named_arguments]]},
 
       # Temporary workers
       {UncatalogedTokenTransfers.Supervisor, [[]]},
diff --git a/config/config.exs b/config/config.exs
index 93e90bc7fe..6631863bce 100644
--- a/config/config.exs
+++ b/config/config.exs
@@ -29,7 +29,8 @@ config :logger,
     {LoggerFileBackend, :indexer},
     {LoggerFileBackend, :indexer_token_balances},
     {LoggerFileBackend, :token_instances},
-    {LoggerFileBackend, :reading_token_functions}
+    {LoggerFileBackend, :reading_token_functions},
+    {LoggerFileBackend, :pending_transactions_to_refetch}
   ]
 
 config :logger, :console,