diff --git a/.gitignore b/.gitignore
index c86fb82db..1d8d1f276 100644
--- a/.gitignore
+++ b/.gitignore
@@ -53,3 +53,6 @@ notes.txt
 
 # TypeScript
 tsout/
+
+# Test results
+test-results/
\ No newline at end of file
diff --git a/app/scripts/lib/buy-url.js b/app/scripts/lib/buy-url.js
index 5a4f2dadf..079d54c39 100644
--- a/app/scripts/lib/buy-url.js
+++ b/app/scripts/lib/buy-url.js
@@ -11,6 +11,7 @@ import {
   MOONPAY_API_KEY,
   COINBASEPAY_API_KEY,
 } from '../constants/on-ramp';
+import { formatMoonpaySymbol } from '../../../ui/helpers/utils/moonpay';
 
 const fetchWithTimeout = getFetchWithTimeout();
 
@@ -75,15 +76,17 @@ const createTransakUrl = (walletAddress, chainId, symbol) => {
  *
  * @param {string} walletAddress - Destination address
  * @param {string} chainId - Current chain ID
+ * @param {string|undefined} symbol - Token symbol to buy
  * @returns String
  */
-const createMoonPayUrl = async (walletAddress, chainId) => {
+const createMoonPayUrl = async (walletAddress, chainId, symbol) => {
   const { moonPay: { defaultCurrencyCode, showOnlyCurrencies } = {} } =
     BUYABLE_CHAINS_MAP[chainId];
   const moonPayQueryParams = new URLSearchParams({
     apiKey: MOONPAY_API_KEY,
     walletAddress,
-    defaultCurrencyCode,
+    defaultCurrencyCode:
+      formatMoonpaySymbol(symbol, chainId) || defaultCurrencyCode,
     showOnlyCurrencies,
   });
   const queryParams = new URLSearchParams({
@@ -159,7 +162,7 @@ export default async function getBuyUrl({ chainId, address, service, symbol }) {
     case 'transak':
       return createTransakUrl(address, chainId, symbol);
     case 'moonpay':
-      return createMoonPayUrl(address, chainId);
+      return createMoonPayUrl(address, chainId, symbol);
     case 'coinbase':
       return createCoinbasePayUrl(address, chainId, symbol);
     case 'metamask-faucet':
diff --git a/app/scripts/lib/buy-url.test.js b/app/scripts/lib/buy-url.test.js
index 188153f6c..2af812ffb 100644
--- a/app/scripts/lib/buy-url.test.js
+++ b/app/scripts/lib/buy-url.test.js
@@ -117,11 +117,11 @@ describe('buy-url', () => {
     nock(SWAPS_API_V2_BASE_URL)
       .get(`/moonpaySign/?${queryParams}`)
       .reply(200, {
-        url: `https://buy.moonpay.com/?apiKey=${MOONPAY_API_KEY}&walletAddress=${MAINNET.address}&defaultCurrencyCode=${defaultCurrencyCode}&showOnlyCurrencies=eth%2Cusdt%2Cusdc%2Cdai&signature=laefTlgkESEc2hv8AZEH9F25VjLEJUADY27D6MccE54%3D`,
+        url: `https://buy.moonpay.com/?apiKey=${MOONPAY_API_KEY}&walletAddress=${MAINNET.address}&defaultCurrencyCode=${defaultCurrencyCode}&showOnlyCurrencies=${showOnlyCurrencies}&signature=laefTlgkESEc2hv8AZEH9F25VjLEJUADY27D6MccE54%3D`,
       });
     const moonPayUrl = await getBuyUrl({ ...MAINNET, service: 'moonpay' });
     expect(moonPayUrl).toStrictEqual(
-      `https://buy.moonpay.com/?apiKey=${MOONPAY_API_KEY}&walletAddress=${MAINNET.address}&defaultCurrencyCode=${defaultCurrencyCode}&showOnlyCurrencies=eth%2Cusdt%2Cusdc%2Cdai&signature=laefTlgkESEc2hv8AZEH9F25VjLEJUADY27D6MccE54%3D`,
+      `https://buy.moonpay.com/?apiKey=${MOONPAY_API_KEY}&walletAddress=${MAINNET.address}&defaultCurrencyCode=${defaultCurrencyCode}&showOnlyCurrencies=${showOnlyCurrencies}&signature=laefTlgkESEc2hv8AZEH9F25VjLEJUADY27D6MccE54%3D`,
     );
     nock.cleanAll();
   });
diff --git a/shared/constants/network.ts b/shared/constants/network.ts
index 45a7d7d03..d09d5e0e6 100644
--- a/shared/constants/network.ts
+++ b/shared/constants/network.ts
@@ -23,11 +23,6 @@ type CurrencySymbol = typeof CURRENCY_SYMBOLS[keyof typeof CURRENCY_SYMBOLS];
  */
 type SupportedCurrencySymbol =
   typeof SUPPORTED_CURRENCY_SYMBOLS[keyof typeof SUPPORTED_CURRENCY_SYMBOLS];
-/**
- * For certain specific situations we need the above type, but with all symbols
- * in lowercase format.
- */
-type LowercaseCurrencySymbol = Lowercase<CurrencySymbol>;
 /**
  * Test networks have special symbols that combine the network name and 'ETH'
  * so that they are distinct from mainnet and other networks that use 'ETH'.
@@ -40,7 +35,7 @@ export type TestNetworkCurrencySymbol =
  * inform the MoonPay API which network the user is attempting to onramp into.
  * This type reflects those possible values.
  */
-type MoonPayNetworkAbbreviation = 'bsc' | 'cchain' | 'polygon';
+type MoonPayNetworkAbbreviation = 'BSC' | 'CCHAIN' | 'POLYGON';
 
 /**
  * MoonPay requires some settings that are configured per network that it is
@@ -49,25 +44,20 @@ type MoonPayNetworkAbbreviation = 'bsc' | 'cchain' | 'polygon';
 type MoonPayChainSettings = {
   /**
    * What should the default onramp currency be, for example 'eth' on 'mainnet'
-   * This type matches a single LowercaseCurrencySymbol or a
-   * LowercaseCurrencySymbol and a MoonPayNetworkAbbreviation joined by a '_'.
+   * This type matches a single SupportedCurrencySymbol or a
+   * SupportedCurrencySymbol and a MoonPayNetworkAbbreviation joined by a '_'.
    */
   defaultCurrencyCode:
-    | LowercaseCurrencySymbol
-    | `${LowercaseCurrencySymbol}_${MoonPayNetworkAbbreviation}`;
+    | SupportedCurrencySymbol
+    | `${SupportedCurrencySymbol}_${MoonPayNetworkAbbreviation}`;
   /**
    * We must also configure all possible onramp currencies we wish to support.
-   * This type matches 1 to 3 LowercaseCurrencySymbols, joined by ','. It also
-   * matches 1 or 2 LowercaseCurrencySymbols with a
-   * MoonPayNetworkAbbreviation joined by a '_', and concatenated with ','.
+   * This type matches either an array of SupportedCurrencySymbol or
+   * an array of SupportedCurrencySymbol and a MoonPayNetworkAbbreviation joined by a '_'.
    */
   showOnlyCurrencies:
-    | `${LowercaseCurrencySymbol}`
-    | `${LowercaseCurrencySymbol},${LowercaseCurrencySymbol}`
-    | `${LowercaseCurrencySymbol},${LowercaseCurrencySymbol},${LowercaseCurrencySymbol}`
-    | `${LowercaseCurrencySymbol},${LowercaseCurrencySymbol},${LowercaseCurrencySymbol},${LowercaseCurrencySymbol}`
-    | `${LowercaseCurrencySymbol}_${MoonPayNetworkAbbreviation}`
-    | `${LowercaseCurrencySymbol}_${MoonPayNetworkAbbreviation},${LowercaseCurrencySymbol}_${MoonPayNetworkAbbreviation}`;
+    | SupportedCurrencySymbol[]
+    | `${SupportedCurrencySymbol}_${MoonPayNetworkAbbreviation}`[];
 };
 
 /**
@@ -318,6 +308,7 @@ const SUPPORTED_CURRENCY_SYMBOLS = {
   ASM: 'ASM',
   AUCTION: 'AUCTION',
   AXS: 'AXS',
+  AVAX: 'AVAX',
   BADGER: 'BADGER',
   BAL: 'BAL',
   BAND: 'BAND',
@@ -351,6 +342,7 @@ const SUPPORTED_CURRENCY_SYMBOLS = {
   GTH: 'GTH',
   HEX: 'HEX',
   IOTX: 'IOTX',
+  IMX: 'IMX',
   JASMY: 'JASMY',
   KEEP: 'KEEP',
   KNC: 'KNC',
@@ -371,6 +363,7 @@ const SUPPORTED_CURRENCY_SYMBOLS = {
   NU: 'NU',
   OGN: 'OGN',
   OMG: 'OMG',
+  ORN: 'ORN',
   OXT: 'OXT',
   PAX: 'PAX',
   PERP: 'PERP',
@@ -685,8 +678,17 @@ export const BUYABLE_CHAINS_MAP: {
       SUPPORTED_CURRENCY_SYMBOLS.YLD,
     ],
     moonPay: {
-      defaultCurrencyCode: 'eth',
-      showOnlyCurrencies: 'eth,usdt,usdc,dai',
+      defaultCurrencyCode: SUPPORTED_CURRENCY_SYMBOLS.ETH,
+      showOnlyCurrencies: [
+        SUPPORTED_CURRENCY_SYMBOLS.ETH,
+        SUPPORTED_CURRENCY_SYMBOLS.USDT,
+        SUPPORTED_CURRENCY_SYMBOLS.USDC,
+        SUPPORTED_CURRENCY_SYMBOLS.DAI,
+        SUPPORTED_CURRENCY_SYMBOLS.MATIC,
+        SUPPORTED_CURRENCY_SYMBOLS.ORN,
+        SUPPORTED_CURRENCY_SYMBOLS.WETH,
+        SUPPORTED_CURRENCY_SYMBOLS.IMX,
+      ],
     },
     wyre: {
       srn: 'ethereum',
@@ -821,8 +823,11 @@ export const BUYABLE_CHAINS_MAP: {
       SUPPORTED_CURRENCY_SYMBOLS.BUSD,
     ],
     moonPay: {
-      defaultCurrencyCode: 'bnb_bsc',
-      showOnlyCurrencies: 'bnb_bsc,busd_bsc',
+      defaultCurrencyCode: `${SUPPORTED_CURRENCY_SYMBOLS.BNB}_BSC`,
+      showOnlyCurrencies: [
+        `${SUPPORTED_CURRENCY_SYMBOLS.BNB}_BSC`,
+        `${SUPPORTED_CURRENCY_SYMBOLS.BUSD}_BSC`,
+      ],
     },
   },
   [CHAIN_IDS.POLYGON]: {
@@ -835,8 +840,11 @@ export const BUYABLE_CHAINS_MAP: {
       SUPPORTED_CURRENCY_SYMBOLS.DAI,
     ],
     moonPay: {
-      defaultCurrencyCode: 'matic_polygon',
-      showOnlyCurrencies: 'matic_polygon,usdc_polygon',
+      defaultCurrencyCode: `${SUPPORTED_CURRENCY_SYMBOLS.BNB}_POLYGON`,
+      showOnlyCurrencies: [
+        `${SUPPORTED_CURRENCY_SYMBOLS.MATIC}_POLYGON`,
+        `${SUPPORTED_CURRENCY_SYMBOLS.USDC}_POLYGON`,
+      ],
     },
     wyre: {
       srn: 'matic',
@@ -848,8 +856,8 @@ export const BUYABLE_CHAINS_MAP: {
     network: 'avaxcchain',
     transakCurrencies: [SUPPORTED_CURRENCY_SYMBOLS.AVALANCHE],
     moonPay: {
-      defaultCurrencyCode: 'avax_cchain',
-      showOnlyCurrencies: 'avax_cchain',
+      defaultCurrencyCode: `${SUPPORTED_CURRENCY_SYMBOLS.AVAX}_CCHAIN`,
+      showOnlyCurrencies: [`${SUPPORTED_CURRENCY_SYMBOLS.AVAX}_CCHAIN`],
     },
     wyre: {
       srn: 'avalanche',
@@ -867,8 +875,8 @@ export const BUYABLE_CHAINS_MAP: {
     network: 'celo',
     transakCurrencies: [SUPPORTED_CURRENCY_SYMBOLS.CELO],
     moonPay: {
-      defaultCurrencyCode: 'celo',
-      showOnlyCurrencies: 'celo',
+      defaultCurrencyCode: SUPPORTED_CURRENCY_SYMBOLS.CELO,
+      showOnlyCurrencies: [SUPPORTED_CURRENCY_SYMBOLS.CELO],
     },
   },
 };
diff --git a/ui/components/app/deposit-popover/deposit-popover.js b/ui/components/app/deposit-popover/deposit-popover.js
index 0a0a814ba..c5ddc363d 100644
--- a/ui/components/app/deposit-popover/deposit-popover.js
+++ b/ui/components/app/deposit-popover/deposit-popover.js
@@ -28,6 +28,7 @@ import {
   getIsBuyableCoinbasePayChain,
   getIsBuyableCoinbasePayToken,
   getIsBuyableTransakToken,
+  getIsBuyableMoonpayToken,
 } from '../../../selectors/selectors';
 
 import OnRampItem from './on-ramp-item';
@@ -53,6 +54,9 @@ const DepositPopover = ({ onClose, token }) => {
   const isTokenBuyableTransak = useSelector((state) =>
     getIsBuyableTransakToken(state, token?.symbol),
   );
+  const isTokenBuyableMoonpay = useSelector((state) =>
+    getIsBuyableMoonpayToken(state, token?.symbol),
+  );
 
   const networkName = NETWORK_TO_NAME_MAP[chainId];
   const symbol = token
@@ -77,7 +81,9 @@ const DepositPopover = ({ onClose, token }) => {
     );
   };
   const toMoonPay = () => {
-    dispatch(buy({ service: 'moonpay', address, chainId }));
+    dispatch(
+      buy({ service: 'moonpay', address, chainId, symbol: token?.symbol }),
+    );
   };
   const toWyre = () => {
     dispatch(buy({ service: 'wyre', address, chainId }));
@@ -153,7 +159,11 @@ const DepositPopover = ({ onClose, token }) => {
           });
           toMoonPay();
         }}
-        hide={isTokenDeposit || !isBuyableMoonPayChain}
+        hide={
+          isTokenDeposit
+            ? !isBuyableMoonPayChain || !isTokenBuyableMoonpay
+            : !isBuyableMoonPayChain
+        }
       />
 
       <OnRampItem
diff --git a/ui/components/app/wallet-overview/token-overview.js b/ui/components/app/wallet-overview/token-overview.js
index 5142c5e8c..f8c7bbf9c 100644
--- a/ui/components/app/wallet-overview/token-overview.js
+++ b/ui/components/app/wallet-overview/token-overview.js
@@ -21,6 +21,7 @@ import {
   getIsSwapsChain,
   getIsBuyableCoinbasePayToken,
   getIsBuyableTransakToken,
+  getIsBuyableMoonpayToken,
 } from '../../../selectors/selectors';
 
 import BuyIcon from '../../ui/icon/overview-buy-icon.component';
@@ -59,7 +60,11 @@ const TokenOverview = ({ className, token }) => {
   const isTokenBuyableTransak = useSelector((state) =>
     getIsBuyableTransakToken(state, token.symbol),
   );
-  const isBuyable = isTokenBuyableCoinbasePay || isTokenBuyableTransak;
+  const isTokenBuyableMoonpay = useSelector((state) =>
+    getIsBuyableMoonpayToken(state, token.symbol),
+  );
+  const isBuyable =
+    isTokenBuyableCoinbasePay || isTokenBuyableTransak || isTokenBuyableMoonpay;
 
   useEffect(() => {
     if (token.isERC721 && process.env.COLLECTIBLES_V1) {
diff --git a/ui/helpers/utils/moonpay.js b/ui/helpers/utils/moonpay.js
new file mode 100644
index 000000000..67686d741
--- /dev/null
+++ b/ui/helpers/utils/moonpay.js
@@ -0,0 +1,19 @@
+import {
+  BUYABLE_CHAINS_MAP,
+  CHAIN_IDS,
+} from '../../../shared/constants/network';
+
+export const formatMoonpaySymbol = (symbol, chainId = CHAIN_IDS.MAINNET) => {
+  if (!symbol) {
+    return symbol;
+  }
+  let _symbol = symbol;
+  if (chainId === CHAIN_IDS.POLYGON || chainId === CHAIN_IDS.BSC) {
+    _symbol = `${_symbol}_${BUYABLE_CHAINS_MAP?.[
+      chainId
+    ]?.network.toUpperCase()}`;
+  } else if (chainId === CHAIN_IDS.AVALANCHE) {
+    _symbol = `${_symbol}_CCHAIN`;
+  }
+  return _symbol;
+};
diff --git a/ui/helpers/utils/moonpay.test.js b/ui/helpers/utils/moonpay.test.js
new file mode 100644
index 000000000..bf13f500d
--- /dev/null
+++ b/ui/helpers/utils/moonpay.test.js
@@ -0,0 +1,33 @@
+import { CHAIN_IDS } from '../../../shared/constants/network';
+import { formatMoonpaySymbol } from './moonpay';
+
+describe('Moonpay Utils', () => {
+  describe('formatMoonpaySymbol', () => {
+    it('should return the same input if falsy input is provided', () => {
+      expect(formatMoonpaySymbol()).toBe(undefined);
+      expect(formatMoonpaySymbol(null)).toBe(null);
+      expect(formatMoonpaySymbol('')).toBe('');
+    });
+
+    it('should return the symbol in uppercase if no chainId is provided', () => {
+      const result = formatMoonpaySymbol('ETH');
+      expect(result).toStrictEqual('ETH');
+    });
+
+    it('should return the symbol in uppercase if chainId is different than Avalanche/BSC/Polygon', () => {
+      const result = formatMoonpaySymbol('ETH', CHAIN_IDS.MAINNET);
+      expect(result).toStrictEqual('ETH');
+      const result2 = formatMoonpaySymbol('CELO', CHAIN_IDS.CELO);
+      expect(result2).toStrictEqual('CELO');
+    });
+
+    it('should return the symbol in uppercase with the network name if chainId is Avalanche/BSC/Polygon', () => {
+      const result = formatMoonpaySymbol('BNB', CHAIN_IDS.BSC);
+      expect(result).toStrictEqual('BNB_BSC');
+      const result2 = formatMoonpaySymbol('MATIC', CHAIN_IDS.POLYGON);
+      expect(result2).toStrictEqual('MATIC_POLYGON');
+      const result3 = formatMoonpaySymbol('AVAX', CHAIN_IDS.AVALANCHE);
+      expect(result3).toStrictEqual('AVAX_CCHAIN');
+    });
+  });
+});
diff --git a/ui/selectors/selectors.js b/ui/selectors/selectors.js
index 961bf339f..78ad6d79d 100644
--- a/ui/selectors/selectors.js
+++ b/ui/selectors/selectors.js
@@ -63,6 +63,7 @@ import {
 } from '../ducks/app/app';
 import { isEqualCaseInsensitive } from '../../shared/modules/string-utils';
 import { hexToDecimal } from '../../shared/lib/metamask-controller-utils';
+import { formatMoonpaySymbol } from '../helpers/utils/moonpay';
 ///: BEGIN:ONLY_INCLUDE_IN(flask)
 import { SNAPS_VIEW_ROUTE } from '../helpers/constants/routes';
 import { getPermissionSubjects } from './permissions';
@@ -716,6 +717,16 @@ export function getIsBuyableTransakToken(state, symbol) {
   );
 }
 
+export function getIsBuyableMoonpayToken(state, symbol) {
+  const chainId = getCurrentChainId(state);
+  const _symbol = formatMoonpaySymbol(symbol, chainId);
+  return Boolean(
+    BUYABLE_CHAINS_MAP?.[chainId]?.moonPay.showOnlyCurrencies?.includes(
+      _symbol,
+    ),
+  );
+}
+
 export function getIsBuyableMoonPayChain(state) {
   const chainId = getCurrentChainId(state);
   return Boolean(BUYABLE_CHAINS_MAP?.[chainId]?.moonPay);