diff --git a/app/_locales/en/messages.json b/app/_locales/en/messages.json
index affb60904..39e111cb7 100644
--- a/app/_locales/en/messages.json
+++ b/app/_locales/en/messages.json
@@ -1735,6 +1735,12 @@
     "message": "You are about to swap $1 $2 (~$3) for $4 $5 (~$6).",
     "description": "This message represents the price slippage for the swap.  $1 and $4 are a number (ex: 2.89), $2 and $5 are symbols (ex: ETH), and $3 and $6 are fiat currency amounts."
   },
+  "swapPriceDifferenceAcknowledgement": {
+    "message": "I'm aware"
+  },
+  "swapPriceDifferenceAcknowledgementNoFiat": {
+    "message": "Continue"
+  },
   "swapPriceDifferenceTitle": {
     "message": "Price difference of ~$1%",
     "description": "$1 is a number (ex: 1.23) that represents the price difference."
diff --git a/ui/app/pages/swaps/view-quote/index.scss b/ui/app/pages/swaps/view-quote/index.scss
index 397748c2a..20c2ea0b4 100644
--- a/ui/app/pages/swaps/view-quote/index.scss
+++ b/ui/app/pages/swaps/view-quote/index.scss
@@ -15,6 +15,11 @@
     padding-right: 20px;
     justify-content: space-between;
 
+    &_modal > div:not(.view-quote__warning-wrapper) {
+      opacity: 0.6;
+      pointer-events: none;
+    }
+
     @media screen and (max-width: 576px) {
       overflow-y: auto;
       max-height: 428px;
@@ -98,14 +103,30 @@
         .actionable-message__message {
           color: inherit;
         }
+
+        button {
+          background: $Yellow-500;
+          border-radius: 42px;
+        }
       }
 
-      &.high .actionable-message {
-        border-color: $Red-500;
-        background: $Red-100;
+      &.high {
+        .actionable-message {
+          border-color: $Red-500;
+          background: $Red-100;
 
-        .actionable-message__message {
-          color: $Red-500;
+          .actionable-message__message {
+            color: $Red-500;
+          }
+        }
+
+        button {
+          background: $Red-500;
+          color: #fff;
+          border-radius: 42px;
+
+          /* Offsets the width of ActionableMessage icon */
+          margin-right: -22px;
         }
       }
 
@@ -118,11 +139,17 @@
 
     &-contents {
       display: flex;
+      text-align: left;
 
       &-title {
         font-weight: bold;
       }
 
+      &-actions {
+        text-align: end;
+        padding-top: 10px;
+      }
+
       i {
         margin-inline-start: 10px;
       }
diff --git a/ui/app/pages/swaps/view-quote/tests/view-quote-price-difference.test.js b/ui/app/pages/swaps/view-quote/tests/view-quote-price-difference.test.js
index bf37e0061..1fc66284b 100644
--- a/ui/app/pages/swaps/view-quote/tests/view-quote-price-difference.test.js
+++ b/ui/app/pages/swaps/view-quote/tests/view-quote-price-difference.test.js
@@ -140,7 +140,7 @@ describe('View Price Quote Difference', function () {
   })
 
   it('displays a fiat error when calculationError is present', function () {
-    const props = { ...DEFAULT_PROPS }
+    const props = { ...DEFAULT_PROPS, priceSlippageUnknownFiatValue: true }
     props.usedQuote.priceSlippage.calculationError =
       'Could not determine price.'
 
diff --git a/ui/app/pages/swaps/view-quote/view-quote-price-difference.js b/ui/app/pages/swaps/view-quote/view-quote-price-difference.js
index 5a3be3cac..bf229b8da 100644
--- a/ui/app/pages/swaps/view-quote/view-quote-price-difference.js
+++ b/ui/app/pages/swaps/view-quote/view-quote-price-difference.js
@@ -2,64 +2,37 @@ import React, { useContext } from 'react'
 
 import PropTypes from 'prop-types'
 import classnames from 'classnames'
-import BigNumber from 'bignumber.js'
-import { useEthFiatAmount } from '../../../hooks/useEthFiatAmount'
 import { I18nContext } from '../../../contexts/i18n'
 
 import ActionableMessage from '../actionable-message'
 import Tooltip from '../../../components/ui/tooltip'
 
 export default function ViewQuotePriceDifference(props) {
-  const { usedQuote, sourceTokenValue, destinationTokenValue } = props
+  const {
+    usedQuote,
+    sourceTokenValue,
+    destinationTokenValue,
+    onAcknowledgementClick,
+    acknowledged,
+    priceSlippageFromSource,
+    priceSlippageFromDestination,
+    priceDifferencePercentage,
+    priceSlippageUnknownFiatValue,
+  } = props
 
   const t = useContext(I18nContext)
 
-  const priceSlippageFromSource = useEthFiatAmount(
-    usedQuote?.priceSlippage?.sourceAmountInETH || 0,
-  )
-  const priceSlippageFromDestination = useEthFiatAmount(
-    usedQuote?.priceSlippage?.destinationAmountInEth || 0,
-  )
-
-  if (!usedQuote || !usedQuote.priceSlippage) {
-    return null
-  }
-
-  const { priceSlippage } = usedQuote
-
-  // We cannot present fiat value if there is a calculation error or no slippage
-  // from source or destination
-  const priceSlippageUnknownFiatValue =
-    !priceSlippageFromSource ||
-    !priceSlippageFromDestination ||
-    priceSlippage.calculationError
-
-  let priceDifferencePercentage = 0
-  if (priceSlippage.ratio) {
-    priceDifferencePercentage = parseFloat(
-      new BigNumber(priceSlippage.ratio, 10)
-        .minus(1, 10)
-        .times(100, 10)
-        .toFixed(2),
-      10,
-    )
-  }
-
-  const shouldShowPriceDifferenceWarning =
-    ['high', 'medium'].includes(priceSlippage.bucket) ||
-    priceSlippageUnknownFiatValue
-
-  if (!shouldShowPriceDifferenceWarning) {
-    return null
-  }
-
   let priceDifferenceTitle = ''
   let priceDifferenceMessage = ''
   let priceDifferenceClass = ''
+  let priceDifferenceAcknowledgementText = ''
   if (priceSlippageUnknownFiatValue) {
     // A calculation error signals we cannot determine dollar value
     priceDifferenceMessage = t('swapPriceDifferenceUnavailable')
     priceDifferenceClass = 'fiat-error'
+    priceDifferenceAcknowledgementText = t(
+      'swapPriceDifferenceAcknowledgementNoFiat',
+    )
   } else {
     priceDifferenceTitle = t('swapPriceDifferenceTitle', [
       priceDifferencePercentage,
@@ -72,7 +45,8 @@ export default function ViewQuotePriceDifference(props) {
       usedQuote.destinationTokenInfo.symbol, // Destination token symbol,
       priceSlippageFromDestination, // Destination tokens total value
     ])
-    priceDifferenceClass = priceSlippage.bucket
+    priceDifferenceClass = usedQuote.priceSlippage.bucket
+    priceDifferenceAcknowledgementText = t('swapPriceDifferenceAcknowledgement')
   }
 
   return (
@@ -92,6 +66,17 @@ export default function ViewQuotePriceDifference(props) {
                 </div>
               )}
               {priceDifferenceMessage}
+              {!acknowledged && (
+                <div className="view-quote__price-difference-warning-contents-actions">
+                  <button
+                    onClick={() => {
+                      onAcknowledgementClick()
+                    }}
+                  >
+                    {priceDifferenceAcknowledgementText}
+                  </button>
+                </div>
+              )}
             </div>
             <Tooltip
               position="bottom"
@@ -111,4 +96,10 @@ ViewQuotePriceDifference.propTypes = {
   usedQuote: PropTypes.object,
   sourceTokenValue: PropTypes.string,
   destinationTokenValue: PropTypes.string,
+  onAcknowledgementClick: PropTypes.func,
+  acknowledged: PropTypes.bool,
+  priceSlippageFromSource: PropTypes.string,
+  priceSlippageFromDestination: PropTypes.string,
+  priceDifferencePercentage: PropTypes.number,
+  priceSlippageUnknownFiatValue: PropTypes.bool,
 }
diff --git a/ui/app/pages/swaps/view-quote/view-quote.js b/ui/app/pages/swaps/view-quote/view-quote.js
index 6a9ab838f..466fb8377 100644
--- a/ui/app/pages/swaps/view-quote/view-quote.js
+++ b/ui/app/pages/swaps/view-quote/view-quote.js
@@ -6,6 +6,7 @@ import { isEqual } from 'lodash'
 import classnames from 'classnames'
 import { I18nContext } from '../../../contexts/i18n'
 import SelectQuotePopover from '../select-quote-popover'
+import { useEthFiatAmount } from '../../../hooks/useEthFiatAmount'
 import { useEqualityCheck } from '../../../hooks/useEqualityCheck'
 import { useNewMetricEvent } from '../../../hooks/useMetricEvent'
 import { useSwapsEthToken } from '../../../hooks/useSwapsEthToken'
@@ -88,6 +89,11 @@ export default function ViewQuote() {
   const [warningHidden, setWarningHidden] = useState(false)
   const [originalApproveAmount, setOriginalApproveAmount] = useState(null)
 
+  const [
+    acknowledgedPriceDifference,
+    setAcknowledgedPriceDifference,
+  ] = useState(false)
+
   const routeState = useSelector(getBackgroundSwapRouteState)
   const quotes = useSelector(getQuotes, isEqual)
   useEffect(() => {
@@ -474,20 +480,70 @@ export default function ViewQuote() {
       : 'ETH',
   ])
 
-  const viewQuotePriceDifferenceComponent = (
-    <ViewQuotePriceDifference
-      usedQuote={usedQuote}
-      sourceTokenValue={sourceTokenValue}
-      destinationTokenValue={destinationTokenValue}
-    />
+  // Price difference warning
+  let viewQuotePriceDifferenceComponent = null
+  const priceSlippageFromSource = useEthFiatAmount(
+    usedQuote?.priceSlippage?.sourceAmountInETH || 0,
+  )
+  const priceSlippageFromDestination = useEthFiatAmount(
+    usedQuote?.priceSlippage?.destinationAmountInEth || 0,
   )
 
+  // We cannot present fiat value if there is a calculation error or no slippage
+  // from source or destination
+  const priceSlippageUnknownFiatValue =
+    !priceSlippageFromSource ||
+    !priceSlippageFromDestination ||
+    usedQuote?.priceSlippage?.calculationError
+
+  let priceDifferencePercentage = 0
+  if (usedQuote?.priceSlippage?.ratio) {
+    priceDifferencePercentage = parseFloat(
+      new BigNumber(usedQuote.priceSlippage.ratio, 10)
+        .minus(1, 10)
+        .times(100, 10)
+        .toFixed(2),
+      10,
+    )
+  }
+
+  const shouldShowPriceDifferenceWarning =
+    !showInsufficientWarning &&
+    usedQuote &&
+    (['high', 'medium'].includes(usedQuote.priceSlippage.bucket) ||
+      priceSlippageUnknownFiatValue)
+
+  if (shouldShowPriceDifferenceWarning) {
+    viewQuotePriceDifferenceComponent = (
+      <ViewQuotePriceDifference
+        usedQuote={usedQuote}
+        sourceTokenValue={sourceTokenValue}
+        destinationTokenValue={destinationTokenValue}
+        priceSlippageFromSource={priceSlippageFromSource}
+        priceSlippageFromDestination={priceSlippageFromDestination}
+        priceDifferencePercentage={priceDifferencePercentage}
+        priceSlippageUnknownFiatValue={priceSlippageUnknownFiatValue}
+        onAcknowledgementClick={() => {
+          setAcknowledgedPriceDifference(true)
+        }}
+        acknowledged={acknowledgedPriceDifference}
+      />
+    )
+  }
+
+  const disableSubmissionDueToPriceWarning =
+    shouldShowPriceDifferenceWarning && !acknowledgedPriceDifference
+
   const isShowingWarning =
-    showInsufficientWarning || viewQuotePriceDifferenceComponent !== null
+    showInsufficientWarning || shouldShowPriceDifferenceWarning
 
   return (
     <div className="view-quote">
-      <div className="view-quote__content">
+      <div
+        className={classnames('view-quote__content', {
+          'view-quote__content_modal': disableSubmissionDueToPriceWarning,
+        })}
+      >
         {selectQuotePopoverShown && (
           <SelectQuotePopover
             quoteDataRows={renderablePopoverData}
@@ -503,7 +559,7 @@ export default function ViewQuote() {
             'view-quote__warning-wrapper--thin': !isShowingWarning,
           })}
         >
-          {!showInsufficientWarning && viewQuotePriceDifferenceComponent}
+          {viewQuotePriceDifferenceComponent}
           {showInsufficientWarning && (
             <ActionableMessage
               message={actionableInsufficientMessage}
@@ -585,6 +641,7 @@ export default function ViewQuote() {
         disabled={
           submitClicked ||
           balanceError ||
+          disableSubmissionDueToPriceWarning ||
           gasPrice === null ||
           gasPrice === undefined
         }